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Discovery of novel transcription factor binding sites by statistical overrepresentation

Understanding the complex and varied mechanisms that regulate gene expression is an important and challenging problem. A fundamental sub-problem is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be co-regulated. We discuss a computational method...

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Detalhes bibliográficos
Main Authors: Sinha, Saurabh, Tompa, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140044/
https://ncbi.nlm.nih.gov/pubmed/12490723
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