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Discovery of novel transcription factor binding sites by statistical overrepresentation

Understanding the complex and varied mechanisms that regulate gene expression is an important and challenging problem. A fundamental sub-problem is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be co-regulated. We discuss a computational method...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Sinha, Saurabh, Tompa, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12490723/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf669
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