Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes

BACKGROUND: Immature B lymphocytes and certain B cell lymphomas undergo apoptotic cell death following activation of the B cell antigen receptor (BCR) signal transduction pathway. Several biochemical changes occur in response to BCR engagement, including activation of the Syk tyrosine kinase. Althou...

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Bibliografske podrobnosti
Main Authors: Hsueh, Robert C, Hammill, Adrienne M, Lee, Jamie A, Uhr, Jonathan W, Scheuermann, Richard H
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2002
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC139997/
https://ncbi.nlm.nih.gov/pubmed/12470302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-3-16
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