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Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes
BACKGROUND: Immature B lymphocytes and certain B cell lymphomas undergo apoptotic cell death following activation of the B cell antigen receptor (BCR) signal transduction pathway. Several biochemical changes occur in response to BCR engagement, including activation of the Syk tyrosine kinase. Althou...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139997/ https://ncbi.nlm.nih.gov/pubmed/12470302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-3-16 |
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