Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes

BACKGROUND: Immature B lymphocytes and certain B cell lymphomas undergo apoptotic cell death following activation of the B cell antigen receptor (BCR) signal transduction pathway. Several biochemical changes occur in response to BCR engagement, including activation of the Syk tyrosine kinase. Althou...

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Pubblicato in:	BMC Immunol
Autori principali:	Hsueh, Robert C, Hammill, Adrienne M, Lee, Jamie A, Uhr, Jonathan W, Scheuermann, Richard H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2002
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139997/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12470302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2172-3-16
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