Changes in the middle region of Sup35 profoundly alter the nature of epigenetic inheritance for the yeast prion [PSI(+)]
The yeast prion [PSI(+)] provides an epigenetic mechanism for the inheritance of new phenotypes through self-perpetuating changes in protein conformation. [PSI(+)] is a nonfunctional, ordered aggregate of the translation termination factor Sup35p that influences new Sup35 proteins to adopt the same...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12461168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252652099 |
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