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The insulation of genes from external enhancers and silencing chromatin

Insulators are DNA sequence elements that can serve in some cases as barriers to protect a gene against the encroachment of adjacent inactive condensed chromatin. Some insulators also can act as blocking elements to protect against the activating influence of distal enhancers associated with other g...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Burgess-Beusse, Bonnie, Farrell, Catherine, Gaszner, Miklos, Litt, Michael, Mutskov, Vesco, Recillas-Targa, Felix, Simpson, Melanie, West, Adam, Felsenfeld, Gary
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Colloquium Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12154228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162342499
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