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The insulation of genes from external enhancers and silencing chromatin
Insulators are DNA sequence elements that can serve in some cases as barriers to protect a gene against the encroachment of adjacent inactive condensed chromatin. Some insulators also can act as blocking elements to protect against the activating influence of distal enhancers associated with other g...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139905/ https://ncbi.nlm.nih.gov/pubmed/12154228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162342499 |
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