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Transmission of prions

The “protein only” hypothesis states that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein predominantly expressed in brain, and is strongly supported by many lines of evidence. Prion diseases are so far unique among conformatio...

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Autori principali: Weissmann, C., Enari, M., Klöhn, P.-C., Rossi, D., Flechsig, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC139897/
https://ncbi.nlm.nih.gov/pubmed/12181490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172403799
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