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Transmission of prions

The “protein only” hypothesis states that the infectious agent causing transmissible spongiform encephalopathies is a conformational isomer of PrP, a host protein predominantly expressed in brain, and is strongly supported by many lines of evidence. Prion diseases are so far unique among conformatio...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Weissmann, C., Enari, M., Klöhn, P.-C., Rossi, D., Flechsig, E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12181490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172403799
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