Casein Kinase II Phosphorylates the Fragile X Mental Retardation Protein and Modulates Its Biological Properties

Fragile X syndrome is caused by loss of FMR1 protein expression. FMR1 binds RNA and associates with polysomes in the cytoplasm; thus, it has been proposed to function as a regulator of gene expression at the posttranscriptional level. Posttranslational modification of FMR1 had previously been sugges...

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Bibliografiske detaljer
Main Authors: Siomi, Mikiko C., Higashijima, Kyoko, Ishizuka, Akira, Siomi, Haruhiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139871/
https://ncbi.nlm.nih.gov/pubmed/12446764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8438-8447.2002
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