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The Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes

The class II transactivator (CIITA) is the key regulator of major histocompatibility complex (MHC) class II gene transcription. We demonstrate here that CIITA requires the ATPase subunit of an hSWI/SNF complex, brahma-related gene 1 (BRG-1), to activate transcription. When introduced into a cell lin...

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Hlavní autoři: Mudhasani, Rajini, Fontes, Joseph D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC139786/
https://ncbi.nlm.nih.gov/pubmed/12077331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.14.5019-5026.2002
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