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The Class II Transactivator Requires brahma-Related Gene 1 To Activate Transcription of Major Histocompatibility Complex Class II Genes

The class II transactivator (CIITA) is the key regulator of major histocompatibility complex (MHC) class II gene transcription. We demonstrate here that CIITA requires the ATPase subunit of an hSWI/SNF complex, brahma-related gene 1 (BRG-1), to activate transcription. When introduced into a cell lin...

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Bibliographische Detailangaben
Hauptverfasser: Mudhasani, Rajini, Fontes, Joseph D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139786/
https://ncbi.nlm.nih.gov/pubmed/12077331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.14.5019-5026.2002
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