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In vitro and in vivo MMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts

BACKGROUND: Members of the matrix metalloproteinase (MMP) family of proteases are required for the degradation of the basement membrane and extracellular matrix in both normal and pathological conditions. In vitro, MT1-MMP (MMP-14, membrane type-1-MMP) expression is higher in more invasive human bre...

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Main Authors: Haupt, Larisa M, Thompson, Erik W, Trezise, Ann EO, Irving, Rachel E, Irving, Michael G, Griffiths, Lyn R
格式: Artigo
語言:Inglês
出版: BioMed Central 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1397851/
https://ncbi.nlm.nih.gov/pubmed/16430785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-18
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