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Insulin Gene Transcription Is Mediated by Interactions between the p300 Coactivator and PDX-1, BETA2, and E47

Pancreatic β-cell-type-specific expression of the insulin gene requires both ubiquitous and cell-enriched activators, which are organized within the enhancer region into a network of protein-protein and protein-DNA interactions to promote transcriptional synergy. Protein-protein-mediated communicati...

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Bibliografiske detaljer
Main Authors: Qiu, Yi, Guo, Min, Huang, Suming, Stein, Roland
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139753/
https://ncbi.nlm.nih.gov/pubmed/11756538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.412-420.2002
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