Genetic Ablation of the Steroid Receptor Coactivator-Ubiquitin Ligase, E6-AP, Results in Tissue-Selective Steroid Hormone Resistance and Defects in Reproduction

The E6-associated protein (E6-AP), although originally identified as a ubiquitin ligase, has recently been shown to function as a coactivator of steroid receptor-dependent gene expression in in vitro assays. In order to determine whether E6-AP acts as a coactivator in vivo, physiological parameters...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Smith, Carolyn L., DeVera, Darryll G., Lamb, Dolores J., Nawaz, Zafar, Jiang, Yong-Hui, Beaudet, Arthur L., O’Malley, Bert W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2002
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.525-535.2002
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