Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

The importance of the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain strains of Neisseria gonorrhoeae was determined by using genetic derivatives of penicillin-sensitive strain FA19 bearing defined mutations (mtrR, penA, and penB) donated by a clinic...

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Autores principales: Veal, Wendy L., Nicholas, Robert A., Shafer, William M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Molecular Biology of Pathogens
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC139619/
https://ncbi.nlm.nih.gov/pubmed/12270819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.20.5619-5624.2002
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