Naïve T-Cell Dynamics in Human Immunodeficiency Virus Type 1 Infection: Effects of Highly Active Antiretroviral Therapy Provide Insights into the Mechanisms of Naïve T-Cell Depletion

Both naïve CD4(+) and naïve CD8(+) T cells are depleted in individuals with human immunodeficiency virus type 1 (HIV-1) infection by unknown mechanisms. Analysis of their dynamics prior to and after highly active antiretroviral therapy (HAART) could reveal possible mechanisms of depletion. Twenty pa...

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Detalhes bibliográficos
Main Authors: Di Mascio, Michele, Sereti, Irini, Matthews, Lynn T., Natarajan, Ven, Adelsberger, Joseph, Lempicki, Richard, Yoder, Christian, Jones, Elizabeth, Chow, Catherine, Metcalf, Julia A., Sidorov, Igor A., Dimitrov, Dimiter S., Polis, Michael A., Kovacs, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395465/
https://ncbi.nlm.nih.gov/pubmed/16501076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.6.2665-2674.2006
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