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A Mutation in the Human Immunodeficiency Virus Type 1 Gag Protein Destabilizes the Interaction of the Envelope Protein Subunits gp120 and gp41

The Gag protein of human immunodeficiency virus type 1 (HIV-1) associates with the envelope protein complex during virus assembly. The available evidence indicates that this interaction involves recognition of the gp41 cytoplasmic tail (CT) by the matrix protein (MA) region of Pr55(Gag). Here we sho...

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Detalhes bibliográficos
Main Authors: Davis, Melody R., Jiang, Jiyang, Zhou, Jing, Freed, Eric O., Aiken, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395406/
https://ncbi.nlm.nih.gov/pubmed/16474147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2405-2417.2006
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