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Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry

In vitro expanded neural stem/progenitor cells can undergo region-specific differentiation after transplantation to the developing or adult brain, and display morphologies and markers characteristic of mature neurons. Here we have used patch-clamp techniques to explore whether grafted stem cells als...

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Autors principals: Englund, Ulrica, Björklund, Anders, Wictorin, Klas, Lindvall, Olle, Kokaia, Merab
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC139274/
https://ncbi.nlm.nih.gov/pubmed/12471158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252589099
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