Role of erythropoietin receptor signaling in Friend virus-induced erythroblastosis and polycythemia

Friend virus is an acutely oncogenic retrovirus that causes erythroblastosis and polycythemia in mice. Previous studies suggested that the Friend virus oncoprotein, gp55, constitutively activates the erythropoietin receptor (EPOR), causing uncontrolled erythroid proliferation. Those studies showed t...

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Detalhes bibliográficos
Main Authors: Zhang, Ji, Randall, Mindy S., Loyd, Melanie R., Li, Weimin, Schweers, Rachel L., Persons, Derek A., Rehg, Jerold E., Noguchi, Constance T., Ihle, James N., Ney, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1392603/
https://ncbi.nlm.nih.gov/pubmed/16174761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1784
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