The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

The complement system is an important component of the innate immune response to bacterial pathogens, including Streptococcus pneumoniae. The classical complement pathway is activated by antibody–antigen complexes on the bacterial surface and has been considered predominately to be an effector of th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Brown, Jeremy S., Hussell, Tracy, Gilliland, Sarah M., Holden, David W., Paton, James C., Ehrenstein, Michael R., Walport, Mark J., Botto, Marina
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477926/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012669199
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