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The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

The complement system is an important component of the innate immune response to bacterial pathogens, including Streptococcus pneumoniae. The classical complement pathway is activated by antibody–antigen complexes on the bacterial surface and has been considered predominately to be an effector of th...

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Detalhes bibliográficos
Main Authors: Brown, Jeremy S., Hussell, Tracy, Gilliland, Sarah M., Holden, David W., Paton, James C., Ehrenstein, Michael R., Walport, Mark J., Botto, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139253/
https://ncbi.nlm.nih.gov/pubmed/12477926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012669199
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