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The promoter of IL-18 binding protein: Activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein β

The IL-18 binding protein (IL-18BP) is a circulating inhibitor of the proinflammatory cytokine IL-18. It is constitutively expressed in mononuclear cells, and elevated expression is induced by IFN-γ. In this study, we characterized the IL-18BP promoter. We first showed that induction is at the trans...

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Detalhes bibliográficos
Main Authors: Hurgin, Vladimir, Novick, Daniela, Rubinstein, Menachem
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139251/
https://ncbi.nlm.nih.gov/pubmed/12482935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262663399
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