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Genetic analysis of iron citrate toxicity in yeast: Implications for mammalian iron homeostasis
Deletion of the yeast homologue of frataxin, YFH1, results in mitochondrial iron accumulation and respiratory deficiency (petite formation). We used a genetic screen to identify mutants that modify iron-associated defects in respiratory activity in Δyfh1 cells. A deletion in the peroxisomal citrate...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139245/ https://ncbi.nlm.nih.gov/pubmed/12471153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232392299 |
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