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Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril

The molecular conformation of peptide fragment 105–115 of transthyretin, TTR(105–115), previously shown to form amyloid fibrils in vitro, has been determined by magic-angle spinning solid-state NMR spectroscopy. (13)C and (15)N linewidth measurements indicate that TTR(105–115) forms a highly ordered...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jaroniec, Christopher P., MacPhee, Cait E., Astrof, Nathan S., Dobson, Christopher M., Griffin, Robert G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12481032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.252625999
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