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A unique molecular chaperone Cosmc required for activity of the mammalian core 1 β3-galactosyltransferase
Human core 1 β3-galactosyltransferase (C1β3Gal-T) generates the core 1 O-glycan Galβ1-3GalNAcα1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in animal glycoproteins. We report here that C1β3Gal-T activity requires expression of a molecular chaperone designated Cosmc (core 1...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139192/ https://ncbi.nlm.nih.gov/pubmed/12464682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262438199 |
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