Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line

INTRODUCTION: Germline mutations in the breast and ovarian cancer susceptibility gene BRCA1, which is located on chromosome 17q21, are associated with a predisposition to the development of cancer in these organs [1,2]. No mutations in the BRCA1 gene have been detected in sporadic breast cancer case...

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Main Authors: Annab, Lois A, Hawkins, Rebecca E, Solomon, Greg, Barrett, J Carl, Afshari, Cynthia A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2000
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC13916/
https://ncbi.nlm.nih.gov/pubmed/11056686
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