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Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca(2+) channel activity

We report here the purification of glycerotoxin from the venom of Glycera convoluta, a novel 320 kDa protein capable of reversibly stimulating spontaneous and evoked neurotransmitter release at the frog neuromuscular junction. However, glycerotoxin is ineffective at the murine neuromuscular junction...

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Detalhes bibliográficos
Main Authors: Meunier, Frédéric A., Feng, Zhong-Ping, Molgó, Jordi, Zamponi, Gerald W., Schiavo, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139097/
https://ncbi.nlm.nih.gov/pubmed/12485994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf677
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