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Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF

The HIV-1 transactivator protein, Tat, is an atypical transcriptional activator that functions through binding, not to DNA, but to a short leader RNA, TAR. Although details of its functional mechanism are still unknown, emerging findings suggest that Tat serves primarily to adapt co-activator comple...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Brès, Vanessa, Tagami, Hideaki, Péloponèse, Jean-Marie, Loret, Erwan, Jeang, Kuan-Teh, Nakatani, Yoshihiro, Emiliani, Stephane, Benkirane, Monsef, Kiernan, Rosemary E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2002
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12486002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf669
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