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Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF

The HIV-1 transactivator protein, Tat, is an atypical transcriptional activator that functions through binding, not to DNA, but to a short leader RNA, TAR. Although details of its functional mechanism are still unknown, emerging findings suggest that Tat serves primarily to adapt co-activator comple...

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Detalhes bibliográficos
Main Authors: Brès, Vanessa, Tagami, Hideaki, Péloponèse, Jean-Marie, Loret, Erwan, Jeang, Kuan-Teh, Nakatani, Yoshihiro, Emiliani, Stephane, Benkirane, Monsef, Kiernan, Rosemary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139090/
https://ncbi.nlm.nih.gov/pubmed/12486002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf669
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