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Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway

When pre-mRNAs are spliced, a multi-component complex is deposited onto them, close to the sites of intron removal. New findings suggest that these exon-exon junction complexes and the complexes that bind mRNA caps are key effectors of the fate of spliced mRNAs and may regulate whether mRNAs contain...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Schell, Thomas, Kulozik, Andreas E, Hentze, Matthias W
Format: Artigo
Langue:Inglês
Publié: BMC 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11897029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2002-3-3-reviews1006
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