Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies

BACKGROUND: Information on major harms of medical interventions comes primarily from epidemiologic studies performed after licensing and marketing. Comparison with data from large-scale randomized trials is occasionally feasible. We compared evidence from randomized trials with that from epidemiolog...

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Main Authors: Papanikolaou, Panagiotis N., Christidi, Georgia D., Ioannidis, John P.A.
Format: Artigo
Sprog:Inglês
Udgivet: Canadian Medical Association 2006
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1389826/
https://ncbi.nlm.nih.gov/pubmed/16505459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.050873
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