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State-dependent Block of CNG Channels by Dequalinium

Cyclic nucleotide–gated (CNG) ion channels are nonselective cation channels with a high permeability for Ca(2+). Not surprisingly, they are blocked by a number of Ca(2+) channel blockers including tetracaine, pimozide, and diltiazem. We studied the effects of dequalinium, an extracellular blocker of...

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Autors principals: Rosenbaum, Tamara, Gordon-Shaag, Ariela, Islas, León D., Cooper, Jeremy, Munari, Mika, Gordon, Sharona E.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1389615/
https://ncbi.nlm.nih.gov/pubmed/14981138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308925
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