Deletion of Individual mRNA Capping Genes Is Unexpectedly Not Lethal to Candida albicans and Results in Modified mRNA Cap Structures

Eukaryotic mRNAs are modified at the 5′ end with a cap structure. In fungal cells, the formation of the mRNA cap structure is catalyzed by three enzymes: triphosphatase, guanylyltransferase, and methyltransferase. Fungal capping enzymes have been proposed to be good antifungal targets because they d...

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Detalhes bibliográficos

Publicado no:	Eukaryot Cell
Principais autores:	Dunyak, Donna S., Everdeen, Daniel S., Albanese, Joseph G., Quinn, Cheryl L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.1.6.1010-1020.2002
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