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Therapeutic Efficacy of PUMA for Malignant Glioma Cells Regardless of the p53 Status
Replacement of the p53 tumor suppressor gene is a rational approach to the management of malignant gliomas because p53 is frequently mutated or inactivated in these cancers. Major weaknesses of this approach are that malignant gliomas are mixtures of cells with wild-type and mutant p53 and that tumo...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1387050/ https://ncbi.nlm.nih.gov/pubmed/15960600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2005.16.685 |
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