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Biomechanics of P-Selectin PSGL-1 Bonds: Shear Threshold and Integrin-Independent Cell Adhesion

Platelet-leukocyte adhesion may contribute to thrombosis and inflammation. We examined the heterotypic interaction between unactivated neutrophils and either thrombin receptor activating peptide (TRAP)-stimulated platelets or P-selectin-bearing beads (Ps-beads) in suspension. Cone-plate viscometers...

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Main Authors: Xiao, Zhihua, Goldsmith, Harry L., McIntosh, Fiona A., Shankaran, Harish, Neelamegham, Sriram
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biophysical Society 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386801/
https://ncbi.nlm.nih.gov/pubmed/16387772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065789
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