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Role of the Met(3534)–Ala(4271) Region of the Ryanodine Receptor in the Regulation of Ca(2+) Release Induced by Calmodulin Binding Domain Peptide
CaMBP, a peptide corresponding to the 3614–3643 calmodulin (CaM) binding region of the ryanodine receptor (RyR1), is known to activate RyR1 Ca(2+) channel. To analyze the mechanism of channel regulation by the CaMBP-RyR1 interaction, we investigated a), CaMBP binding to RyR1, b), induced local confo...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biophysical Society
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1386780/ https://ncbi.nlm.nih.gov/pubmed/16387763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.074328 |
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