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Mutually Exclusive Expression of Virulence Genes by Malaria Parasites Is Regulated Independently of Antigen Production

The primary virulence determinant of Plasmodium falciparum malaria parasite–infected cells is a family of heterogeneous surface receptors collectively referred to as PfEMP1. These proteins are encoded by a large, polymorphic gene family called var. The family contains approximately 60 individual gen...

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Bibliographic Details
Main Authors: Dzikowski, Ron, Frank, Matthias, Deitsch, Kirk
Format: Artigo
Language:Inglês
Published: Public Library of Science 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386720/
https://ncbi.nlm.nih.gov/pubmed/16518466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020022
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