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Variable switching rates of malaria virulence genes are associated with chromosomal position and gene subclass

Antigenic variation in Plasmodium falciparum malaria is mediated by transcriptional switches between different members of the multicopy var gene family. Each var gene encodes a member of a group of heterogeneous surface proteins collectively referred to as PfEMP1. Mutually exclusive expression ensur...

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Detalhes bibliográficos
Main Authors: Frank, Matthias, Dzikowski, Ron, Amulic, Borko, Deitsch, Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634120/
https://ncbi.nlm.nih.gov/pubmed/17555435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05736.x
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