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Variable switching rates of malaria virulence genes are associated with chromosomal position and gene subclass

Antigenic variation in Plasmodium falciparum malaria is mediated by transcriptional switches between different members of the multicopy var gene family. Each var gene encodes a member of a group of heterogeneous surface proteins collectively referred to as PfEMP1. Mutually exclusive expression ensur...

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Détails bibliographiques
Auteurs principaux: Frank, Matthias, Dzikowski, Ron, Amulic, Borko, Deitsch, Kirk
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634120/
https://ncbi.nlm.nih.gov/pubmed/17555435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05736.x
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