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Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity

BACKGROUND: Sumoylation has emerged as an important posttranslational regulatory mechanism for transcription factors and cofactors. Sumoylation of many transcription factors represses their transcriptional activities. The myocyte enhancer factor 2 (MEF2) family of transcription factors plays an impo...

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Detalhes bibliográficos
Main Authors: Kang, Jungseog, Gocke, Christian B, Yu, Hongtao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386686/
https://ncbi.nlm.nih.gov/pubmed/16478538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-7-5
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