Lack of effect of cimetidine on the pharmacokinetics of bupivacaine in healthy subjects.

1. The possibility of a pharmacokinetic interaction between the H2-receptor antagonist cimetidine and the long-acting local anaesthetic agent bupivacaine was studied in seven healthy, non-smoking volunteers. 2. The study consisted of two sessions at a minimum interval of 4 days. In a randomized, cro...

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Bibliographic Details
Main Authors: Pihlajamäki, K K, Lindberg, R L, Jantunen, M E
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386561/
https://ncbi.nlm.nih.gov/pubmed/3190990
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