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Effect of valpromide on the pharmacokinetics of carbamazepine-10, 11-epoxide.

The single oral dose pharmacokinetics of carbamazepine-10, 11-epoxide (CBZ-E) were investigated in six normal volunteers during a control session and during concurrent treatment with valpromide (VPM) (300 mg twice daily for 8 days). VPM caused a prolongation of the CBZ-E half-life from 6.4 +/- 1.4 t...

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Detalhes bibliográficos
Main Authors: Pisani, F, Fazio, A, Oteri, G, Spina, E, Perucca, E, Bertilsson, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386437/
https://ncbi.nlm.nih.gov/pubmed/3136790
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