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Inhibition by erythromycin of the conversion of carbamazepine to its active 10,11-epoxide metabolite.

The serum levels of carbamazepine (CBZ) and its 10,11-epoxide metabolite (CBZ-E) were determined in seven subjects after a single dose of CBZ (400 mg) in the control state and during co-administration of erythromycin (500 mg three times daily for 10 days). Erythromycin treatment was associated with...

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Detalhes bibliográficos
Main Authors: Barzaghi, N, Gatti, G, Crema, F, Monteleone, M, Amione, C, Leone, L, Perucca, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386415/
https://ncbi.nlm.nih.gov/pubmed/3440106
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