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Ran GTPase Cycle and Importins α and β Are Essential for Spindle Formation and Nuclear Envelope Assembly in Living Caenorhabditis elegans Embryos

The small GTPase Ran has been found to play pivotal roles in several aspects of cell function. We have investigated the role of the Ran GTPase cycle in spindle formation and nuclear envelope assembly in dividing Caenorhabditis elegans embryos in real time. We found that Ran and its cofactors RanBP2,...

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Main Authors: Askjaer, Peter, Galy, Vincent, Hannak, Eva, Mattaj, Iain W.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC138639/
https://ncbi.nlm.nih.gov/pubmed/12475958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-06-0346
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