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Lack of effect of smoking on the metabolism and pharmacokinetics of quinidine in patients.

The urinary metabolite profile of quinidine and the oral clearance of this drug were studied under steady state conditions in five smoking and nine non-smoking patients. No significant differences were observed in the urinary recovery of unchanged quinidine, 3S-3-hydroxyquinidine, 2'-oxoquinidi...

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Autors principals: Edwards, D J, Axelson, J E, Visco, J P, vanEvery, S, Slaughter, R L, Lalka, D
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386236/
https://ncbi.nlm.nih.gov/pubmed/3567051
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