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RAPAMYCIN INHIBITS LIVER GROWTH DURING REFEEDING IN THE RAT VIA CONTROL OF RIBOSOMAL PROTEIN TRANSLATION BUT NOT CAP-DEPENDENT TRANSLATION INITIATION

We have examined the role of the mammalian target of rapamycin (mTOR) in hepatic cell growth. In order to dissociate cell growth from cell proliferation, we employed an in vivo model of non-proliferative liver growth in the rat, refeeding following 48 h of food deprivation. Starvation resulted in a...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anand, Padmanabhan, Gruppuso, Philip A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386153/
https://ncbi.nlm.nih.gov/pubmed/16365054
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