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Liver X receptors as integrators of metabolic and inflammatory signaling

The liver X receptors (LXRs) are nuclear receptors that play central roles in the transcriptional control of lipid metabolism. LXRs function as nuclear cholesterol sensors that are activated in response to elevated intracellular cholesterol levels in multiple cell types. Once activated, LXRs induce...

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Bibliographic Details
Main Authors: Zelcer, Noam, Tontonoz, Peter
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386115/
https://ncbi.nlm.nih.gov/pubmed/16511593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27883
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