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Evidence for polymorphic oxidation of sparteine in Japanese subjects.

The metabolism of sparteine which exhibits a genetic polymorphism in Caucasians was studied in 84 unrelated Japanese subjects. In contrast to a recent study where debrisoquine was used as a probe and no poor metabolizers could be observed in Japanese involving 100 subjects, two subjects had a urinar...

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Detalhes bibliográficos
Main Authors: Ishizaki, T, Eichelbaum, M, Horai, Y, Hashimoto, K, Chiba, K, Dengler, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386100/
https://ncbi.nlm.nih.gov/pubmed/3580254
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