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Antipyrine metabolism in relation to polymorphic oxidations of sparteine and debrisoquine.

Thirty-five healthy subjects who had been classified as extensive or poor metabolizers of both sparteine and debrisoquine were given a single oral dose of antipyrine. Saliva concentration of antipyrine and urinary excretion of its three major oxidation metabolites were measured. All the parameters o...

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Autors principals: Eichelbaum, M, Bertilsson, L, Säwe, J
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427783/
https://ncbi.nlm.nih.gov/pubmed/6849767
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