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Naproxen pharmacokinetics in patients with rheumatoid arthritis during active polyarticular inflammation.

Patients with rheumatoid arthritis often have hypoalbuminaemia as a sign of disease activity. In view of the extensive binding of naproxen to albumin, the pharmacokinetics of total and unbound drug were studied in eight patients and eight healthy male volunteers during chronic intake of 500 mg twice...

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Detalhes bibliográficos
Main Authors: van den Ouweland, F A, Franssen, M J, van de Putte, L B, Tan, Y, van Ginneken, C A, Gribnau, F W
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386067/
https://ncbi.nlm.nih.gov/pubmed/3828195
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